Plasmablastic Myeloma versus Plasmablastic Lymphoma: Different Yet Related Diseases
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چکیده
منابع مشابه
Plasmablastic Myeloma versus Plasmablastic Lymphoma: Different Yet Related Diseases
Plasmablastic myeloma (PBM) is a rare, monoclonal, immunoproliferative plasma cell neoplasm that shares many characteristics with plasmablastic lymphoma (PBL) [1]. Currently, there are no set standards for differentiating between PBL and PBM. Morphologically, PBM is characterized by the presence of large plasma cells with large hyperchromatic nuclei, one or more prominent centrally-located nucl...
متن کاملPlasmablastic Myeloma versus Plasmablastic Lymphoma: Different Yet Related Diseases
Plasmablastic myeloma (PBM) is a rare, monoclonal, immunoproliferative plasma cell neoplasm that shares many characteristics with plasmablastic lymphoma (PBL) [1]. Currently, there are no set standards for differentiating between PBL and PBM. Morphologically, PBM is characterized by the presence of large plasma cells with large hyperchromatic nuclei, one or more prominent centrally-located nucl...
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which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 54-year-old woman was admitted with compression fracture of thoracic vertebral bodies. Urine protein electro-phoresis revealed the presence of M protein and serum free κ/λ ratio was 0.01. Bone marrow aspiration (A) and biopsy (B) revealed diffuse infiltrat...
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B-cell lymphomas with plasmablastic features are a heterogeneous group of lymphomas. While they may share overlapping morphologic or immunophenotypic features, distinct clinicopathologic or molecular genetic features exist for some that have allowed their recognition as distinct entities. Session 2 of the 2009 Society for Hematopathology/European Association for Haematopathology Workshop dealt ...
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Plasmablastic lymphoma (PBL) is an aggressive subtype of DLBCL, first reported in HIV-infected patients1 and subsequently recognized in the WHO 2008 classification.2 PBL often arises in the oral cavity, but other sites include the nasal cavity, GI tract, skin, bone, and lungs.3-5 PBL mainly affects those with immunodeficiency,3-5 but can affect some immunocompetent individuals.6 Histologically,...
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ژورنال
عنوان ژورنال: Hematology & Transfusion International Journal
سال: 2018
ISSN: 2469-2778
DOI: 10.15406/htij.2018.06.00146